You may find more opportunity with small and mid-size firms that do not use internships as a tool for testing out full-time hires for after graduation. While you should not exclude larger companies, do not forget about the smaller entities.
Consider the U.S. Employment landscape to determine industries or companies that operate in a space with high demand for workers. For example, currently there is a high demand (not enough qualified candidates) in the technology/IT sector.
The more specialized skills you possess the more attractive you will be to potential employers. Consider any opportunity to enhance your technical, academic, or “niche” skills.
If applicable, leverage your skills in your native language or other languages you may know – particularly those in high demand. You may wish to target industries, companies, and positions that require fluency in a particular language. In addition, research companies and identify if there is a strong presence in a country where you speak the language. Even if it is not a direct requirement of a particular position it can often help you stand out from other candidates.